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Tamoxifen - Side Effects, Dosage, Interactions. Q: Does tamoxifen cause weight gain? A: Generally, tamoxifen tends to cause weight loss, not weight gain. Patients should contact their health care provider for any changes in their medical condition, including unusual weight gain. You may also find helpful information at http: //www.
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Q: Does tamoxifen ever cause intestinal upset? A: According to the package insert, tamoxifen can cause some gastrointestinal side effects, including abdominal cramps, nausea, diarrhea, constipation and upset stomach. You are encouraged to report any negative side effects of prescription drugs to your healthcare practitioner and the Food and Drug Administration (FDA) by visiting www. FDA- 1. 08. 8. For more information about tamoxifen, please consult with your healthcare practitioner and visit http: //www. Michelle Mc. Dermott, Pharm.
All of the estrogen inhibiting drugs CAN cause hair loss, including Tamoxifen. I guess that's a triple whammy for me. How to Lose Weight While on Tamoxifen. Discuss weight loss with an oncologist and ask about healthy weights for your body type. Commonly reported side effects of tamoxifen include: amenorrhea, fluid retention, hot flash, nausea, vaginal discharge, vaginal hemorrhage, weight loss, and skin. I was surprised when I got my first prescription of Tamoxifen and it said in the papers that it can cause weight LOSS, after hearing so many talk about.
DQ: Can tamoxifen cause high blood sugar? A: According to the package insert, tamoxifen citrate (Nolvadex) does not have elevated blood sugar as a side effect that was reported during clinical trials or that has been reported after the drug was put to market. Post market research of tamoxifen (Nolvadex) does note a rare incidence of increased cholesterol and triglycerides, but not blood sugar. Please see the following Everyday Health link for more information on tamoxifen (Nolvadex). It only happens in the morning when I'm ready to get up. I've just started taking tamoxifen. Are the cramps one its possible side effects?
Read about the cancer treatment drug tamoxifen, also called Soltamox, including what it is, how it works and possible side effects.
Tamoxifen and Arimidex. On the day I was diagnosed I was already 2kg over my preferred weight. Now after a year on Tamoxifen and two. Find a comprehensive guide to possible side effects including common and rare side effects when taking Nolvadex (Tamoxifen Citrate) for healthcare professionals and. Though the overall occurrence of side effects is relatively low among women who take tamoxifen, the following side effects have been reported.
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A: Leg cramps are a common complaint among patients who take tamoxifen. It may help to make sure you stay hydrated throughout the day, and increase your intake of foods containing potassium. You can also ask your physician if drinking tonic water would be an acceptable treatment, since tonic water contains small amounts of quinine, which may take the edge off your cramps. In any case, discuss this side effect with your physician. For more information about tamoxifen, go to http: //www. Matt Curley, Pharm. DQ: I have to make a decision on taking tamoxifen and I am concerned about the side effects of blood clots, vision and other cancers.
I am not sure the risks are worth the risks of changing the quality of my life if I suffer with side effects. My system is very sensitive to drugs in general. A: The results of therapy with any drug can be both positive and negative and it is always important to weight the potential benefits against the potential risks of treatment. Depending on your diagnosis, and reason for taking tamoxifen, the benefits may be well proven. You should discuss these with your healthcare provider to have a full understanding of them and then evaluate them against the risks. According to the package insert, tamoxifen is generally well tolerated, with the most common side effects being hot flashes, vaginal dryness and a mild vaginal discharge. The risk of more serious side effects has been evaluated in scientific studies.
Over a period of nearly 7 years, the risk of uterine cancer in people taking tamoxifen is approximately 2 per 1,0. The risk of blood clots, including stroke and pulmonary embolism, is about 1- 1. For more information, please contact your healthcare provider. Michelle Mc. Dermott, Pharm. DQ: Does tamoxifen cause fluid retention? A: According to drug information, peripheral edema (swelling in the lower limbs), as a side effect, has been reported in 1. Fluid retention was also reported at 3.
As always, talk with your healthcare provider regarding possible side effects of your medication. Jen Marsico, RPh. Q: I'm taking tamoxifen and have been given conflicting information. Do I need to avoid foods that contain phytoestrogens? A: Your question regards avoiding phytoestrogen foods while taking tamoxifen (Nolvadex) http: //www.
Phytoestrogen foods are foods that are structurally similar to estrogen. Tamoxifen works by binding to estrogen receptors in the breast and other tissues to decrease the effects of estrogen.
After performing an extensive search and review of clinical studies concerning phytoestrogens and tamoxifen, it is discovered that there is limited data and appears that additional studies need to be performed to fully understand if this combination is safe. A journal article from 2. American Cancer Society's Web site states that there are animal studies indicating that a specific phytoestrogen could interfere with the effects of tamoxifen on breast cancer cells. Please talk with your health care provider, preferably your oncologist for additional information regarding eating phytoestrogen foods while taking tamoxifen. Jennyfer Marsico, RPh.
Q: I've experienced a racing heart and irregular heartbeat. Can tamoxifen cause these symptoms? A: According to the package insert, common side effects of tamoxifen include bone pain, constipation, coughing, hot flashes, muscle pain, nausea, tiredness, vaginal discharge, and weight loss.
A review of medical literature did not show reports of rapid heart rate (or tachycardia) or irregular heartbeat in patients taking tamoxifen. You are encouraged to report any negative side effects of prescription drugs to your health care practitioner and the Food and Drug Administration (FDA) by visiting www. FDA- 1. 08. 8. For more information, please consult with your health care provider and visit http: //www. Michelle Mc. Dermott, Pharm.
DQ: When my doctor put me on tamoxifen a year and a half ago, he told me not to eat soy products. I have ulcerative colitis and had been taking an over the counter pill (Digestive Advantage for Colon Health) that worked well. A few months ago I noticed in the ingredient list that selenium (soy) was listed. I quit taking it but now my symptons have come back.
Is there an over the counter product that does not contain soy? I was on Pentasa for several years (1. I don't want to go back on Pentasa if there is something else that will help. A: Soy has potential estrogen- like properties, so people receiving drugs like tamoxifen, which block the effects of estrogen, are often told to avoid soy products. The list of ingredients for Digestive Advantage for Colon Health shows that the product includes the following: Di Calcium Phosphate, Ganeden.
BC3. 0 (Bacillus coagulans GBI- 3. Saccharomyces Boulardii, Sodium Starch Glycolate, Silicone Dioxide, Magnesium Stearate, Vitamins A, B, C, D, E, Folic Acid (Folate), Selenium (Soy), Lysine, FD& C Red 4. FD& C Blue 1. The primary component is Ganeden. BC3. 0 - a probiotic of. Q: Can I lose weight while taking Tamoxifen?
A: Studies have shown their can be a change in weight either losing or gaining depending on each individual who takes this medication. Report any abnormal changes in your weight to your health care provider. To help control the weight gain you may want to eat a lot of fruits,vegetables,grains, low fat or fat free milk and their products. Also fish, beans, eggs, poultry, fish and lean meats. Try to get 3. 0 minutes of exercise daily if possible.
Limit you fat and trans fat intake and avoid Alcohol. You may ask your provider what type of diet you should be on to try and help you lose any weight gain. Ask you pharmacist about any interaction diet plans may have with medications your are taking. I have include some sites for you to look at but be sure to let your provider know any diet you may begin. Levy, RPh. Q: Are there any drugs or supplements that interfere with tamoxifen? A: There are numerous drugs that have possible interactions with tamoxifen. The following is a list of some of the medications that can interact with tamoxifen: Blood thinners (Coumadin, warfarin) HIV/AIDS medications (Rescriptor, Norvir), heart rhythm medications (amiodarone or quinidine) antidepressants (Wellbutrin, Cymbalta, Prozac, imipramine, Paxil, Zoloft) Keep in mind that this list is not complete and there are other interactions that may occur.
It is always good to check with your doctor or pharmacist about specific medications you may be concerned with, so that you can get a more specific answer. Megan Uehara, Pharm. DQ: I am a breast cancer survivor taking tamoxifen 2. There isn't any warning on the label, but I heard that I should avoid products containing soy.
Does this mean anything containing soy or just things like soybeans and soymilk? A: According to the American Cancer Society, the possible problem with soy products is the phytoestrogens that are contained in soy products, such as genistein. The fear is that these phytoestrogens could act as estrogen in the body. Phytoestrogens could possibly make tamoxifen less effective which could theoretically result in the growth of breast cancer cells. Researchers have stated that better studies need to be performed to fully understand the extent of this possible interaction and to determine what doses of genistein will affect tamoxifen.
However, researchers recommend that women who are taking tamoxifen should exercise caution with genistein. As always, talk with your health care provider regarding the questions and concerns you have about soy and your medical history and medications.
Jen Marsico RPh www. June 6, 2. 01. 0.
There are no known drug interactions with these medications. Taking all three medications at one time may cause stomach upset. If this is the case, it.
Q: Does tamoxifen cause weight gain? A: Soltamox (tamoxifen) (http: //www. Some cancers such as breast cancer need estrogen to grow. Tamoxifen is used for breast cancer and in women who are at a high risk of developing breast cancer. Common side effects of tamoxifen include hot flashes, depressed mood, nausea, headache and thinning of the hair. A search of prescribing information did list weight loss and possibly weight gain as side effects of Tamoxifen.
Drugs can cause weight gain in several different ways. Some can increase appetite or make you crave certain types of foods like those high in carbohydrates or fat. Other medications may slow down metabolism or cause fluid retention. However, the effect of prescription drugs on body weight is complex.